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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 459377Generated: October 29, 2026

4-(Trifluoromethyl)phenol → HCID 58822666, compound

https://huagongshe.com/reaction/459377

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Trifluoromethyl)phenolHCID 67874—
Reactant(2S)-3-[4-(2-bromo-ethoxy)-phenyl]2-methoxy-propionic acid ethyl esterHCID 58822865—
Reactant(2S)-2-methoxy-3-[4-(3-phenoxy propoxy)-phenyl]-propionic acidHCID 58822897—
ProductHCID 58822666HCID 58822666—

Reaction Steps

The title compound was prepared from (2S)-3-[4-(2-bromo-ethoxy)-phenyl]-2-methoxy-propionic acid ethyl ester (Example 283, Step 2) and 4-trifluoromethyl-phenol via the same procedure used for the preparation of (2S)-2-methoxy-3-[4-(3-phenoxy-propoxy)-phenyl]-propionic acid (Example 285, Step 1), to produce a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07192982B2
Source datasetuspto-grants-2007_03
ORD IDord-1b2b022f13444e50ad8937f270e43fc7
Source noteuspto-grants-2007_03