HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Cumylphenol → (2S)-2-methoxy-3-(4-{2-[4-(1-methyl-1-phenyl-ethyl)-phenoxy]-ethoxy}-phenyl)-propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Cumylphenol | HCID 11742 | — |
| Reactant | (2S)-3-[4-(2-bromo-ethoxy)-phenyl]2-methoxy-propionic acid ethyl ester | HCID 58822865 | — |
| Reactant | (2S)-2-methoxy-3-[4-(3-phenoxy propoxy)-phenyl]-propionic acid | HCID 58822897 | — |
| Product | (2S)-2-methoxy-3-(4-{2-[4-(1-methyl-1-phenyl-ethyl)-phenoxy]-ethoxy}-phenyl)-propionic acid | HCID 58822878 | — |
Reaction Steps
The title compound was prepared from (2S)-3-[4-(2-bromo-ethoxy)-phenyl]-2-methoxy-propionic acid ethyl ester (Example 283, Step 2) and 4-(1-methyl-1-phenyl-ethyl)-phenol via the same procedure used for the preparation of (2S)-2-methoxy-3-[4-(3-phenoxy-propoxy)-phenyl]-propionic acid (Example 285, Step 1), to produce a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07192982B2 |
| Source dataset | uspto-grants-2007_03 |
| ORD ID | ord-66cc518c30d34093b1f91a411390f980 |
| Source note | uspto-grants-2007_03 |