[1,1'-Biphenyl]-4-ol, 4'-(1,1-dimethylethyl)- → (2S)-3-{4-[2-(4'-tert-butyl-biphenyl-4-yloxy)-ethoxy]-phenyl}-2-methoxy-propionic acid

Participants

Reaction Steps

The title compound was prepared from (2S)-3-[4-(2-bromo-ethoxy)-phenyl]-2-methoxy-propionic acid ethyl ester Example 283, Step 2) and 4′-tert-butyl-biphenyl-4-ol via the same procedure used for the preparation of (2S)-2-methoxy-3-[4-(3-phenoxy-propoxy)-phenyl]-propionic acid (Example 285, Step 1), to produce a white solid.

Provenance & Evidence