3-(4-Benzyloxy-phenyl)-2-ethoxy-acrylic acid methyl ester → Ethyl 3-[4-(benzyloxy)phenyl]-2-ethoxyprop-2-enoate

HRID 459394Notes

Reaction equation

HRID 459394 reaction equation
[CH2:1]([O:3][C:4](=[O:25])[CH:5]([O:22][CH2:23][CH3:24])[CH:6]([C:8]1[CH:13]=[CH:12][C:11]([O:14][CH2:15][C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)=[CH:10][CH:9]=1)O)[CH3:2].COC(=O)C(OCC)=CC1C=CC(OCC2C=CC=CC=2)=CC=1>>[CH2:1]([O:3][C:4](=[O:25])[C:5]([O:22][CH2:23][CH3:24])=[CH:6][C:8]1[CH:13]=[CH:12][C:11]([O:14][CH2:15][C:16]2[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=2)=[CH:10][CH:9]=1)[CH3:2]

Participants

3

Reactant 2

HCID 544136053-(4-Benzyloxy-phenyl)-2-ethoxy-acrylic acid methyl esterHCID 58822578Ethyl 3-[4-(benzyloxy)phenyl]-2-ethoxy-3-hydroxypropanoate

Product 1

HCID 54423854Ethyl 3-[4-(benzyloxy)phenyl]-2-ethoxyprop-2-enoate

Procedure

The title compound was prepared from 3-(4-benzyloxy-phenyl)-2-ethoxy-3-hydroxy-propionic acid ethyl ester (Example 375, Step 1) via the same procedure used for the preparation of 3-(4-benzyloxy-phenyl)-2-ethoxy-acrylic acid methyl ester. MS (ES) for C20H22O4 [M+H]+: 327.2.

Sources & evidence

ORD record
ord-8e5394485c01429fa557fb72834ba46d
Source dataset
uspto-grants-2007_03
Patent number
US07192982B2

Reaction notes

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