反应详情

The title compound was prepared from 3-(4-benzyloxy-phenyl)-2-ethoxy-acrylic acid ethyl ester (Example 375, Step 2) (3.3 gr, 10.12 mmol) via the same procedure used for the preparation of 3-(3-benzyloxy-phenyl)-2-methoxy-propionic acid methyl ester (Example 291, Step 3) to produce an oil that was purified by chromatography (silica gel, hexanes/ethyl acetate 6:1) to produce two compounds: 3-(4-benzyloxy-phenyl)-propionic acid methyl ester (1.5 gr, Rf aprox. 0.65) and the desired compound (1.5 gr, Rf aprox. 0.2).

1. customto produce an oil that
2. customwas purified by chromatography (silica gel, hexanes/ethyl acetate 6:1)
3. customto produce two compounds