3-(3-Benzyloxyphenyl)-2-ethoxyacrylic acid ethyl ester → 3-(3-Benzyloxy-phenyl)-2-ethoxy-propionic acid methyl ester

HRID 459403Notes

Reaction equation

HRID 459403 reaction equation
[CH2:1]([O:3][C:4](=[O:24])[C:5]([O:21][CH2:22][CH3:23])=[CH:6][C:7]1[CH:12]=[CH:11][CH:10]=[C:9]([O:13][CH2:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH:8]=1)C.COC(=O)C(OC)CC1C=CC=C(OCC2C=CC=CC=2)C=1>>[CH3:1][O:3][C:4](=[O:24])[CH:5]([O:21][CH2:22][CH3:23])[CH2:6][C:7]1[CH:12]=[CH:11][CH:10]=[C:9]([O:13][CH2:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH:8]=1

Participants

3

Reactant 2

HCID 540313813-(3-Benzyloxyphenyl)-2-ethoxyacrylic acid ethyl esterHCID 588226203-(3-Benzyloxy-phenyl)-2-methoxy-propionic acid methyl ester

Product 1

HCID 588227613-(3-Benzyloxy-phenyl)-2-ethoxy-propionic acid methyl ester

Procedure

The title compound was prepared from 3-(3-benzyloxy-phenyl)-2-ethoxy-acrylic acid ethyl ester Example 378, Step 2) via the same procedure used for the preparation of 3-(3-benzyloxy-phenyl)-2-methoxy-propionic acid methyl ester (Example 291, Step 3) to afford the title compound as a colorless oil.

Sources & evidence

ORD record
ord-218d0a5d5b284ace81a810dfbc7fbe7b
Source dataset
uspto-grants-2007_03
Patent number
US07192982B2

Reaction notes

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