化工社化工社 化学情報印刷レポート · 研究参考用
Acetic Acid → 1,1,1-Trifluoro-8-phenyl-3,5,7-octatrien-2-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetic Acid | HCID 176 | — |
| 反応物 | Piperidine | HCID 8082 | — |
| 反応物 | Methyl trifluoromethyl ketone | HCID 9871 | — |
| 反応物 | 2,4-Pentadienal, 5-phenyl- | HCID 114651 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | 1,1,1-Trifluoro-8-phenyl-3,5,7-octatrien-2-one | HCID 86222662 | — |
反応手順
1,1,1-Trifluoro-8-phenyl-3,5,7-octatrien-2-one is prepared as outlined in Scheme IIIA. 1,1,1-Trifluoro-8-phenyl-3,5,7-octatrien-2-one is prepared by reacting 5-phenyl-2,4-pentadienal in THF with an equal amount of acetic acid and piperidine followed by addition of 1,1,1-trifluoroacetone at room temperature under nitrogen.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07193105B2 |
| 出典データセット | uspto-grants-2007_03 |
| ORD ID | ord-f7731148df1d40508236a4a1e9c5f0a3 |
| 出典メモ | uspto-grants-2007_03 |