tert-Butyl [(1S,2R)-2-azidocyclohexyl]carbamate → (1S,2R)-Cyclohexane-1,2-diamine, N1-BOC protected

Participants

Reaction Steps

(1R,2S)-1-Azido-2-(tert-butoxycarbonylamino)-cyclohexane (174 mg) was dissolved in methanol (10 ml), and to the solution 10% palladium on carbon (120 mg) was added to conduct catalytic reduction under atmospheric pressure. The catalyst was separated by filtration, and the filtrate was concentrated to obtain a crude title compound (145 mg) as a colorless amorphous substance. This compound was used in the next reaction without purifying it.

Provenance & Evidence