HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 23712813, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | Ethyl 1-isopropylpiperidine-4-carboxylate | HCID 19900430 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 23712813 | HCID 23712813 | 100% |
Reaction Steps
Ethyl 1-isopropylpiperidine-4-carboxylate (Farmaco., 1993, Vol. 48, p. 1439) (3.43 g) was dissolved in tetrahydrofuran (60 ml), and water (15 ml) and lithium hydroxide (421 mg) were added at room temperature to stir the mixture overnight. The reaction mixture was concentrated under reduced pressure to obtain the title compound (3.05 g) as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07192968B2 |
| Source dataset | uspto-grants-2007_03 |
| ORD ID | ord-d343047cab2a490991646e4f47ef370c |
| Source note | uspto-grants-2007_03 |