HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 68911497, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 5-Fluoroindole-2-carboxylic acid | HCID 1820 | — |
| Reactant | HCID 58822229 | HCID 58822229 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 68911497 | HCID 68911497 | — |
Reaction Steps
(1S,2R,4R)-N1-tert-Butoxycarbonyl-4-methoxycarbonyl-N2-[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]-1,2-cyclohexanediamine was treated with a 4N dioxane solution of hydrochloric acid and then condensed with 5-fluoroindole-2-carboxylic acid in a similar manner to Example 118 to obtain the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07192968B2 |
| Source dataset | uspto-grants-2007_03 |
| ORD ID | ord-b271f062b7f141a88693532cb87651d2 |
| Source note | uspto-grants-2007_03 |