HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 67056629, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Lithium 5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylate | HCID 23704331 | — |
| Reactant | HCID 86593067 | HCID 86593067 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 67056629 | HCID 67056629 | — |
Reaction Steps
(1S,2R,4S)-N2-(tert-Butoxycarbonyl)-N1-[(6-chloro-4-fluoroindol-2-yl)carbonyl]-4-(N,N-dimethylcarbamoyl)-1,2-cyclohexanediamine was treated with a 4N dioxane solution of hydrochloric acid and then condensed with lithium 5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylate in a similar manner to Example 118 to obtain the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07192968B2 |
| Source dataset | uspto-grants-2007_03 |
| ORD ID | ord-0876a6940c3e4751ab8e1d9c23ec04bc |
| Source note | uspto-grants-2007_03 |