反应详情

The thus obtained 3-methylbutyl glycidyl ether (100 g), acetone (200 ml) and a 3% sulfuric acid aqueous solution (100 ml) were refluxed for 2 hours. Then, after concentration at 50° C./26 hPa, toluene (200 ml) was added to the residue and the resulting mixture was washed with a 3% sodium hydroxide aqueous solution (170 g). The mixture was further washed with saturated brine (150 g) three times and concentrated, and the concentrate was purified by distillation to give 3-methylbutoxypropane-1,2-diol (63 g) (bp: 115–116° C./2.6 hPa).

1. concentrationThen, after concentration at 50° C./26 hPa, toluene (200 ml)
2. additionwas added to the residue
3. washthe resulting mixture was washed with a 3% sodium hydroxide aqueous solution (170 g)
4. washThe mixture was further washed with saturated brine (150 g) three times
5. concentrationconcentrated
6. distillationthe concentrate was purified by distillation