Trifluoroacetic acid → HCID 69352775, compound

Participants

Reaction Steps

4-(2-Benzenesulfonyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-piperazine-1-carboxylic acid tert-butyl ester (1.76 mg) from Step 5 was dissolved in 3 mL of trifluoroacetic acid (TFA) and heated briefly via steam bath. Excess TFA was removed in vacuo, and the residue was recrystallized from absolute ethanol to yield 83 mg of 2-Benzenesulfonyl-5-piperazin-1-yl-1,2,3,4-tetrahydroisoquinoline trifluoroacetic acid salt as a white solid, MP=214–216° C., MS M+H=358.

Provenance & Evidence