HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 459834Generated: October 30, 2026
Dimethylformamide → HCID 86594262, compound
https://huagongshe.com/reaction/459834
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| Reactant | Methyl 2-methyl-3-nitrobenzoate | HCID 601165 | — |
| Product | HCID 86594262 | HCID 86594262 | — |
Reaction Steps
2-Methyl-3-nitro-benzoic acid methyl ester (5.0 g, 25.6 mmol) was combined with dimethoxymethyl-dimethyl-amine (10.2 mL, 76.8 mmol, 3.0 eq.) and DMF (25 mL) and heated to 110° C. overnight. The reaction mixture was then concentrated in vacuo to yield crude 2-(2-Dimethylamino-vinyl)-3-methyl-benzoic acid methyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07196088B2 |
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| Source dataset | uspto-grants-2007_03 |
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| ORD ID | ord-15ea4dda352b4f308d305efc330b3875 |
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| Source note | uspto-grants-2007_03 |
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