Triethylamine → HCID 58824203, compound

Participants

Reaction Steps

To a stirred solution of 4-(biphenyl-4-yloxymethyl)-5-methyl-furan-2-sulphonic acid amide (45) (50 mg, 0.146 mmoles) in dichloromethane (5.0 ml) was added triethylamine (26 μl, 0.189 mmoles), dimethyl-pyridin-4-yl-amine (1 mg) and butyryl chloride (19 μl, 0.184 mmoles). After stirring for 16 hours at room temperature the reaction mixture was concentrated in-vacuo, and the residue was purified by HPLC to give compound 61 as as an off-white solid (48 mg). LC/MS System C: Rt=3.82 mins, m/z (ES−)=412 ((M−H) for C22H23NO5S).

Provenance & Evidence