HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(Quinolin-4-yl)ethan-1-one → 1-(1-Methyl-1H-indol-4-yl)ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(Quinolin-4-yl)ethan-1-one | HCID 12340190 | — |
| Reactant | 1-(1-Methyl-1H-indol-4-yl)-ethanol | HCID 22391398 | — |
| Catalyst | Manganese oxide | HCID 160959 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 1-(1-Methyl-1H-indol-4-yl)ethanone | HCID 14987288 | — |
Reaction Steps
The title compound was prepared by the same procedure for 1-quinolin-4-yl-ethanone from 1-(1-Methyl-1H-indol-4-yl)-ethanol (3.0 g, 17 mmol), manganese oxide (8.69 g, 100 mmol, Aldrich) and dichloromethane (50 mL). The crude title compound was obtained in form as yellow oil in 98% yield (2.9 g, 16.7 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07196102B2 |
| Source dataset | uspto-grants-2007_03 |
| ORD ID | ord-09670b8ea03e4fe19b82605e2f6e6e08 |
| Source note | uspto-grants-2007_03 |