HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → Sodium Azide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 2-(3-Pyridyl)thiazole-4-carboxylic acid | HCID 736513 | — |
| Reactant | 2-(4-Pyridinyl)-4-thiazolylcarbonylazide | HCID 18771740 | — |
| Solvent | Water | HCID 962 | — |
| Product | Sodium Azide | HCID 33557 | — |
| Product | 3-Azidopyridine | HCID 12066687 | — |
Reaction Steps
In a manner similar to that described for the preparation of 2-(4-pyridinyl)-4-thiazolylcarbonylazide, 6.0 g of 2-(3-pyridinyl)-4-thiazolylcarboxylic acid was treated successively with NaOH, oxalyl chloride and a solution of NaN3 in water to give the 3-pyridinylazide as a pale brown solid. MS m/z: 204.5 (M−N2+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07196104B2 |
| Source dataset | uspto-grants-2007_03 |
| ORD ID | ord-71f97e4564f9488fb60f42ca14a3b848 |
| Source note | uspto-grants-2007_03 |