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HRID460179

反应详情

EQUATION

反应方程式

HRID 460179 的结构方程式

REACTANTS

反应物

4
结构：S
HCID402

Hydrogen sulfide

H2S

结构：CCOC(=O)C(=O)CBr
HCID66144

Propanoic acid, 3-bromo-2-oxo-, ethyl ester

C5H7BrO3

结构：N#Cc1ccc(S(=O)(=O)N2CCOCC2)cc1
HCID4132823

4-(morpholin-4-ylsulfonyl)benzonitrile

C11H12N2O3S

结构：NS(=O)(=O)c1ccc(-c2nc(C(=O)O)cs2)cc1
HCID18772085

未命名化合物

PRODUCTS

生成物

1
结构：O=C(O)c1csc(-c2ccc(S(=O)(=O)N3CCOCC3)cc2)n1
HCID18771739

未命名化合物

PROCEDURE

实验过程

In a manner similar to that described for the preparation of 2-(4-aminosulfonylphenyl)thiazole-4-carboxylic acid, 460 mg of 4-(morpholinosulfonyl)-benzonitrile was treated with H2S, ethyl bromopyruvate, and LIOH successively to give the title compound. MS m/z: 355 (M+H).