HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 460320Generated: October 30, 2026
4-Piperidinecarboxylic acid → HCID 69143578, compound
https://huagongshe.com/reaction/460320
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Piperidinecarboxylic acid | HCID 3773 | — |
| Reactant | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Reactant | HCID 18445940 | HCID 18445940 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 69143578 | HCID 69143578 | — |
Reaction Steps
The mixture of 310 mg of 1-(5-chloro-4-nitrothiophene-2-sulfonyl)piperidine, 250 mg of piperidine-4-carboxylic acid and 3 ml of NMP is stirred at 85° C. for 1 h, cooled, diluted with 15 ml of water and stirred. The precipitate is filtered off with suction, washed with water and recrystallized from isopropanol/water (4:1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07196114B2 |
|---|
| Source dataset | uspto-grants-2007_03 |
|---|
| ORD ID | ord-917c8717f34c4f12967907aebdd0d12d |
|---|
| Source note | uspto-grants-2007_03 |
|---|
