Tolylboronic acid → 1,4-Bis[5-(4-methylphenyl)-2-pyridyl]hexahydro-1,4-diazepine

Participants

Reaction Steps

Following the procedure of Example 1, crude crystals were obtained from the 1,4-bis(5-bromo-2-pyridyl)hexahydro-1,4-diazepine (206.0 mg, 0.500 mmol) synthesized in Reference Example 1 and 4-methylphenylboronic acid (163.0 mg, 1.20 mmol). The crude crystals were recrystallized from chloroform-hexane to yield the title compound as pale yellow needles (melting point: 245.0–247.0° C.)(93.0 mg, yield: 42%).

Provenance & Evidence