HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic acid 3-benzyloxycarbonylamino-4-oxo-azetidin-2-yl ester → Acetic acid 3-amino-4-oxo-azetidin-2-yl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic acid 3-benzyloxycarbonylamino-4-oxo-azetidin-2-yl ester | HCID 13124490 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | Acetic acid 3-amino-4-oxo-azetidin-2-yl ester | HCID 19350682 | — |
Reaction Steps
Acetic acid 3-benzyloxycarbonylamino-4-oxo-azetidin-2-yl ester (100 mg, 0.36 mmol) was hydrogenated on a Parr shaker over 10% palladium on carbon (100 mg) in ethyl acetate (20 ml) at 50 psi for 5 h. The mixture was filtered through Celite and evaporated. Acetic acid 3-amino-4-oxo-azetidin-2-yl ester was obtained in quantitative yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07196099B2 |
| Source dataset | uspto-grants-2007_03 |
| ORD ID | ord-3cfe61c790c5448d851567369623ad4d |
| Source note | uspto-grants-2007_03 |