反应详情

p-nitrophenyl-β-D-glucopyranoside (Tokyo Chemical Industries) (250 mg) was dissolved in a methanol/tetrahydrofuran mixed solvent (20 ml/5 ml), and 10% palladium carbon (250 mg) was added to this solution. Hydrogen gas was introduced under a nitrogen gas atmosphere into the reaction solution at room temperature for 3 hours. The reaction mixture was filtered to remove palladium carbon, the filtrate was evaporated under vacuum, and solidified. This residue was purified by silica gel chromatography using a tetrahydrofuran/chloroform mixed solvent (1/1, volume ratio) as an eluant, and p-aminophenol-β-D-glucopyranoside was obtained.

1. additionwas added to this solution
2. filtrationThe reaction mixture was filtered
3. customto remove palladium carbon
4. customthe filtrate was evaporated under vacuum
5. customThis residue was purified by silica gel chromatography