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Ethyl 2-(6,6,7,7,7-pentafluoroheptyl)-8-nonenoate → 10-[3,17beta-Dihydroxyestra-1,3,5(10)-trien-7alpha-yl]-2-(6,6,7,7,7-pentafluoroheptyl)decanoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethyl 2-(6,6,7,7,7-pentafluoroheptyl)-8-nonenoate | HCID 22718078 | — |
| 反応物 | 3-Methoxy-7alpha-(2-propenyl)estra-1,3,5(10)-trien-17beta-ol | HCID 69414807 | — |
| 生成物 | 10-[3,17beta-Dihydroxyestra-1,3,5(10)-trien-7alpha-yl]-2-(6,6,7,7,7-pentafluoroheptyl)decanoic acid | HCID 86588530 | — |
反応手順
Starting with the 3-methoxy-7α-(2-propenyl)estra-1,3,5(10)-trien-17β-ol prepared in Example 13 and ethyl 2-(6,6,7,7,7-pentafluoroheptyl)-8-nonenoate prepared separately, the same procedure as shown in Example 13 was repeated to give 10-[3,17β-dihydroxyestra-1,3,5(10)-trien-7α-yl]-2-(6,6,7,7,7-pentafluoroheptyl)decanoic acid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07196081B2 |
| 出典データセット | uspto-grants-2007_03 |
| ORD ID | ord-a3d7e40c76434b51860df903da69928a |
| 出典メモ | uspto-grants-2007_03 |