Ethyl 2-(4,4,5,5,5-pentafluoropentyl)-8-nonenoate → 10-(3,17beta-Dihydroxyestra-1,3,5(10)-trien-11beta-yl)-2-(4,4,5,5,5-pentafluoropentyl)decanoic acid

Participants

Reaction Steps

Starting with the 3,17β-bis(benzyloxy)-11-(2-propenyl) estra-1,3,5(10),9(11)-tetraene prepared in Example 20 and ethyl 2-(4,4,5,5,5-pentafluoro-pentyl)-8-nonenoate prepared separately, the same procedure as shown in Example 20 was repeated to give 10-(3,17β-dihydroxyestra-1,3,5(10)-trien-11β-yl)-2-(4,4,5,5,5-pentafluoropentyl)decanoic acid.

Provenance & Evidence