Thionyl Chloride → HCID 11289887, compound

Participants

Reaction Steps

A few drops of dimethylformamide were added to a solution of 63 g (0.22 mol) of 2-methyl-3,4-di(methylsulfonyl)benzoic acid in 550 ml of toluene, and 36 g (0.3 mol) of thionyl chloride were then added dropwise. The reaction mixture was heated at reflux for 1.5 hours. After cooling, the reaction mixture was concentrated. This gave 62 g (93% yield) of 2-methyl-3,4-di(methylsulfonyl)benzoyl chloride as a beige solid.

Provenance & Evidence