3-Methoxypropylamine → N-(3-Methoxypropyl)-6-[[2-(morpholin-4-yl)-1-phenyl-1H-benzimidazol-6-yl]oxy]Hexanamide

HRID 460530Notes

Reaction equation

HRID 460530 reaction equation
CO[C:3](=[O:31])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][O:9][C:10]1[CH:11]=[CH:12][C:13]2[N:17]=[C:16]([N:18]3[CH2:23][CH2:22][O:21][CH2:20][CH2:19]3)[N:15]([C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)[C:14]=2[CH:30]=1.[CH3:32][O:33][CH2:34][CH2:35][CH2:36][NH2:37]>>[CH3:32][O:33][CH2:34][CH2:35][CH2:36][NH:37][C:3](=[O:31])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][O:9][C:10]1[CH:11]=[CH:12][C:13]2[N:17]=[C:16]([N:18]3[CH2:19][CH2:20][O:21][CH2:22][CH2:23]3)[N:15]([C:24]3[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=3)[C:14]=2[CH:30]=1

Participants

3

Reactant 2

HCID 16723-MethoxypropylamineHCID 102958696-[[2-(Morpholin-4-yl)-1-phenyl-1H-benzimidazol-6-yl]oxy]Hexanoic Acid Methyl Ester

Product 1

HCID 10299492N-(3-Methoxypropyl)-6-[[2-(morpholin-4-yl)-1-phenyl-1H-benzimidazol-6-yl]oxy]Hexanamide

Procedure

135 mg of 6-[[2-(morpholin4-yl)-1-phenyl-1H-benzimidazol-6-yl]oxy]hexanoic acid methyl ester was reacted with 3-methoxypropylamine according to general operating instructions 4. 94 mg was obtained.

Workup

  1. custom94 mg was obtained

Sources & evidence

ORD record
ord-88cc3d19bbea4848b2ed3b1889d59ff2
Source dataset
uspto-grants-2007_03
Patent number
US07196202B2

Reaction notes

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