HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Naphthalen-2-yl)piperidine → ethyl (S)-7-(2-hydroxy-3-(4-(naphthalen-2-yl)piperidino)propyloxy)benzo(b)furan-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Naphthalen-2-yl)piperidine | HCID 22029264 | — |
| Reactant | ethyl (S)-7-(glycidyloxy)benzo(b)furan-2-carboxylate | HCID 86585640 | — |
| Product | ethyl (S)-7-(2-hydroxy-3-(4-(naphthalen-2-yl)piperidino)propyloxy)benzo(b)furan-2-carboxylate | HCID 60077908 | 77.3% |
Reaction Steps
By the reactions in the same manner as in Starting Material Synthesis Example 11 using ethyl (S)-7-(glycidyloxy)benzo(b)furan-2-carboxylate (5.3 g) and 4-(naphthalen-2-yl)piperidine (3.0 g), the title compound (5.2 g) was obtained as a brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07196199B2 |
| Source dataset | uspto-grants-2007_03 |
| ORD ID | ord-21b098ff6bb2424684f71519495d1967 |
| Source note | uspto-grants-2007_03 |