2-Benzofurancarbonitrile, 4-methoxy- → 1-(Hydroxyimino)-1-(4-methoxybenzo(b)furan-2-yl)methylamine

Participants

Reaction Steps

To a solution (40 ml) of 4-methoxybenzo(b)furan-2-carbonitrile (2.8 g) in ethanol were added hydroxylamine hydrochloride (1.2 g) and sodium hydrogencarbonate (3.0 g). The mixture was refluxed under heating for 1.5 hr. The inorganic material was filtered off and the reaction mixture was concentrated under reduced pressure to give the title compound (3.4 g) as brown crystals.

Provenance & Evidence