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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 460569Generated: October 30, 2026

7-Methoxybenzofuran-2-carbonitrile → 1-(Hydroxyimino)-1-(7-methoxybenzo(b)furan-2-yl)methylamine

https://huagongshe.com/reaction/460569

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-Methoxybenzofuran-2-carbonitrileHCID 298556—
ReactantHydroxyamine hydrochlorideHCID 443297—
ReactantSodium BicarbonateHCID 516892—
Product1-(Hydroxyimino)-1-(7-methoxybenzo(b)furan-2-yl)methylamineHCID 306947092.4%

Reaction Steps

By the reactions in the same manner as in Starting Material Synthesis Example 28 using 7-methoxybenzo(b)furan-2-carbonitrile (3.0 g), hydroxylamine hydrochloride (1.4 g) and sodium hydrogencarbonate (2.1 g), the title compound (3.3 g) was obtained as brown crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07196199B2
Source datasetuspto-grants-2007_03
ORD IDord-eca6e16760354c3da092a460468d06be
Source noteuspto-grants-2007_03