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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 460613Generated: October 29, 2026

Potassium Carbonate → (s)-4-Glycidyloxy-2-(1-methylimidazol-2-yl)benzo(b)furan

https://huagongshe.com/reaction/460613

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
Reactant(S)-(+)-Glycidyl-4-nitrobenzoateHCID 10868995—
Reactant4-Hydroxy-2-(1-methylimidazol-2-yl)benzo(b)furanHCID 135794322—
Product(s)-4-Glycidyloxy-2-(1-methylimidazol-2-yl)benzo(b)furanHCID 60077993—

Reaction Steps

By the reactions in the same manner as in Starting Material Synthesis Example 1 using 4-hydroxy-2-(1-methylimidazol-2-yl)benzo(b)furan (1.10 g), (S)-glycidyl nosylate (1.33 g) and potassium carbonate (2.13 g), a crude product of the title compound was quantitatively obtained as a pale-yellow oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07196199B2
Source datasetuspto-grants-2007_03
ORD IDord-d2847cc7f8d343c89d4e21b9bce263a1
Source noteuspto-grants-2007_03