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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 460615Generated: October 29, 2026

Potassium Carbonate → (s)-4-Glycidyloxy-2-(5-methyloxazol-2-yl)benzo(b)thiophene

https://huagongshe.com/reaction/460615

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
Reactant(S)-(+)-Glycidyl-4-nitrobenzoateHCID 10868995—
Reactant4-Hydroxy-2-(5-methyloxazol-2-yl)benzo(b)thiopheneHCID 135794311—
Product(s)-4-Glycidyloxy-2-(5-methyloxazol-2-yl)benzo(b)thiopheneHCID 60078115—

Reaction Steps

By the reactions in the same manner as in Starting Material Synthesis Example 1 using 4-hydroxy-2-(5-methyloxazol-2-yl)benzo(b)thiophene (2.20 g), (S)-glycidyl nosylate (2.38 g) and potassium carbonate (3.18 g), a crude product of the title compound was quantitatively obtained as pale-yellow crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07196199B2
Source datasetuspto-grants-2007_03
ORD IDord-0addd2f1082540ec9c26b71197607fc2
Source noteuspto-grants-2007_03