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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 460641Generated: October 29, 2026

4-(3,4-Dimethoxyphenyl)piperidine → (S)-1-(4-(3,4-dimethoxyphenyl)piperidino)-3-(2-(5-methyl-1,3,4-oxadiazol-2-yl)benzo(b)furan-4-yloxy)-2-propanol

https://huagongshe.com/reaction/460641

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(3,4-Dimethoxyphenyl)piperidineHCID 545828—
Reactant(S)-5-(4-glycidyloxybenzo(b)furan-2-yl)-2-methyl-1,3,4-oxadiazoleHCID 60078060—
Product(S)-1-(4-(3,4-dimethoxyphenyl)piperidino)-3-(2-(5-methyl-1,3,4-oxadiazol-2-yl)benzo(b)furan-4-yloxy)-2-propanolHCID 6007811149%

Reaction Steps

By the reactions in the same manner as in Example 1 using (S)-5-(4-glycidyloxybenzo(b)furan-2-yl)-2-methyl-1,3,4-oxadiazole (0.90 g) and 4-(3,4-dimethoxyphenyl)piperidine (0.90 g); the title compound (0.80 g) was obtained as a brown oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07196199B2
Source datasetuspto-grants-2007_03
ORD IDord-e675806210a844fea14ba133d4c98c62
Source noteuspto-grants-2007_03