HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(3,4-Dimethoxyphenyl)piperidine → (S)-1-(4-(3,4-dimethoxyphenyl)piperidino)-3-(2-(5-methyl-1,3,4-oxadiazol-2-yl)benzo(b)furan-4-yloxy)-2-propanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(3,4-Dimethoxyphenyl)piperidine | HCID 545828 | — |
| Reactant | (S)-5-(4-glycidyloxybenzo(b)furan-2-yl)-2-methyl-1,3,4-oxadiazole | HCID 60078060 | — |
| Product | (S)-1-(4-(3,4-dimethoxyphenyl)piperidino)-3-(2-(5-methyl-1,3,4-oxadiazol-2-yl)benzo(b)furan-4-yloxy)-2-propanol | HCID 60078111 | 49% |
Reaction Steps
By the reactions in the same manner as in Example 1 using (S)-5-(4-glycidyloxybenzo(b)furan-2-yl)-2-methyl-1,3,4-oxadiazole (0.90 g) and 4-(3,4-dimethoxyphenyl)piperidine (0.90 g); the title compound (0.80 g) was obtained as a brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07196199B2 |
| Source dataset | uspto-grants-2007_03 |
| ORD ID | ord-e675806210a844fea14ba133d4c98c62 |
| Source note | uspto-grants-2007_03 |