HuagongsheHuagongshe Chemistry Print Report · For research reference only
m-Tolyl isocyanate → HCID 12608480, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | m-Tolyl isocyanate | HCID 69303 | — |
| Reactant | Ether hydrochloride | HCID 10953452 | — |
| Reactant | 3-[2-(4-Aminopiperidyl)ethyl]indole, hydrate | HCID 20384353 | — |
| Product | HCID 12608480 | HCID 12608480 | 83.2% |
Reaction Steps
Condensation of 3-[2-(4-Aminopiperidyl)ethyl]indole, hydrate (1.31 g.) and 3-tolyl isocyanate (0.70 g., 5% excess) in the manner of Example 1 gave the crude title compound (1.70 g.) from which was obtained a pure hydrochloride (1.57 g., m.p. 228.9°, dec.) by treatment with ethanolic HCl/ether.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04061641 |
| Source dataset | uspto-grants-1977_12 |
| ORD ID | ord-96dc184380b143a6ab2d6eb128e93d66 |
| Source note | uspto-grants-1977_12 |