HuagongsheHuagongshe Chemistry Print Report · For research reference only
beta-Aminobeta-ethoxyacrylic acid ethyl ester → 3-Amino-1-(3-fluorobenzyl)-pyrazol-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | beta-Aminobeta-ethoxyacrylic acid ethyl ester | HCID 278451 | — |
| Reactant | 3-Fluorobenzylhydrazine | HCID 16778346 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-Amino-1-(3-fluorobenzyl)-pyrazol-5-one | HCID 20367249 | — |
Reaction Steps
17.5 g of β-amino-β-ethoxyacrylic acid ethyl ester and 13 g of 3-fluorobenzylhydrazine, on stirring for 5 hours in ethanol at 60° and working up as described in Example 1, yield 11.3 g, corresponding to 55% of theory, of the compound identified above as colorless crystals of melting point 129°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04061653 |
| Source dataset | uspto-grants-1977_12 |
| ORD ID | ord-81487a1aa44b4edabe99fd9d9dfdf629 |
| Source note | uspto-grants-1977_12 |