Morpholine → 5-isopropyl-2-morpholin-4-yl-1,3-oxazol-4(5H)-one

HRID 46089Notes

Reaction equation

HRID 46089 reaction equation

[NH2:1][C:2]1[O:3][CH:4]([CH:8]([CH3:10])[CH3:9])[C:5](=[O:7])[N:6]=1.N1[CH2:16][CH2:15][O:14][CH2:13][CH2:12]1>>[CH:8]([CH:4]1[O:3][C:2]([N:1]2[CH2:16][CH2:15][O:14][CH2:13][CH2:12]2)=[N:6][C:5]1=[O:7])([CH3:10])[CH3:9]

Participants

3

Reactant 2

HCID 8083Morpholine

HCID 49617292-amino-5-isopropyl-1,3-oxazol-4(5H)-one

Product 1

HCID 589301525-isopropyl-2-morpholin-4-yl-1,3-oxazol-4(5H)-one

Procedure

Synthesis was performed from 2-amino-5-isopropyl-1,3-oxazol-4(5H)-one and morpholine according to Method G+H.

Workup

customSynthesis

Sources & evidence

ORD record: ord-78712f63f5d54645b325c440224fa93a
Source dataset: uspto-grants-2013_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08541592B2

Reaction notes

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