beta-Aminobeta-ethoxyacrylic acid ethyl ester → HCID 20367316, compound

HRID 460920Notes

Reaction equation

C([O:3][C:4](=O)[CH:5]=[C:6]([NH2:10])OCC)C.[Cl:12][C:13]1[CH:21]=[CH:20][CH:19]=[CH:18][C:14]=1[CH2:15][NH:16][NH2:17]>>[NH2:10][C:6]1[NH:17][N:16]([CH2:15][C:14]2[CH:18]=[CH:19][CH:20]=[CH:21][C:13]=2[Cl:12])[C:4](=[O:3])[CH:5]=1

Participants

Reactant 2

HCID 278451beta-Aminobeta-ethoxyacrylic acid ethyl ester

HCID 4170642-Chlorobenzylhydrazine

Product 1

HCID 20367316HCID 20367316, compoundYield 40%

Procedure

35 g of β-amino-β-ethoxyacrylic acid ethyl ester and 32 g of 2-chlorobenzylhydrazine when reacted as described in Example 45 yield 17.5 g of the compound identified above as colorless crystals of melting point 153°. (Yield: 40% of theory)

Sources & evidence

ORD record: ord-020fbd10e35344158917c1250bc033eb
Source dataset: uspto-grants-1977_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04061653

Reaction notes

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