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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 461035Generated: October 25, 2026

rac-(1R,2R)-2-phenylcyclopentan-1-amine hydrochloride → N-[(1R,2S)-2-phenylcyclopentyl]azepan-2-imine;hydrochloride

https://huagongshe.com/reaction/461035

Reaction equation

Participants

RoleNameHCIDCharge
Reactantrac-(1R,2R)-2-phenylcyclopentan-1-amine hydrochlorideHCID 70051154—
Reactanttrans-2-Phenylcyclopentan-1-amine hydrochlorideHCID 70053696—
ProductN-[(1R,2S)-2-phenylcyclopentyl]azepan-2-imine;hydrochlorideHCID 145795654—

Reaction Steps

Following the procedure of Example 23, only substituting for cis-2-phenylcyclopentylamine hydrochloride the appropriate molar equivalent amount of trans-2-phenylcyclopentylamine hydrochloride, M.P. 147°-149° C, the desired product is obtained, M.P. 192°-195° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04061746
Source datasetuspto-grants-1977_12
ORD IDord-9eb7408f316b495283435674883c402c
Source noteuspto-grants-1977_12