HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexylamine, 2-phenyl-, hydrochloride, trans- → N-[(1R,2S)-2-phenylcyclohexyl]azepan-2-imine;hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexylamine, 2-phenyl-, hydrochloride, trans- | HCID 209556 | — |
| Reactant | rac-(1R,2R)-2-phenylcyclopentan-1-amine hydrochloride | HCID 70051154 | — |
| Product | N-[(1R,2S)-2-phenylcyclohexyl]azepan-2-imine;hydrochloride | HCID 145795666 | — |
Reaction Steps
Following the procedure of Example 23, only substituting for cis-2-phenylcyclopentylamine hydrochloride an appropriate amount of trans-2-phenylcyclohexylamine hydrochloride, M.P. 251° -257° C, and employing a reaction time of 38 days, the desired product is obtained, M.P. 236°-239° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04061746 |
| Source dataset | uspto-grants-1977_12 |
| ORD ID | ord-7df08f1c2d934730b4e4341281fc2bf8 |
| Source note | uspto-grants-1977_12 |