2-Imidazolidinethione, 4,4-dimethyl- → HCID 22760449, compound

HRID 461138Notes

Reaction equation

HRID 461138 reaction equation
[Br:1][CH2:2][C:3]([C:5]1[CH:10]=[CH:9][C:8]([Cl:11])=[C:7]([S:12](=[O:15])(=[O:14])[NH2:13])[CH:6]=1)=[O:4].[CH3:16][C:17]1([CH3:23])[CH2:21][NH:20][C:19](=[S:22])[NH:18]1>CO>[BrH:1].[Cl:11][C:8]1[CH:9]=[CH:10][C:5]([C:3]2([OH:4])[CH2:2][S:22][C:19]3=[N:18][C:17]([CH3:23])([CH3:16])[CH2:21][N:20]23)=[CH:6][C:7]=1[S:12](=[O:15])(=[O:14])[NH2:13]

Participants

4

Reactant 2

HCID 30325022-Imidazolidinethione, 4,4-dimethyl-HCID 12952390Bromo-4'-chloro-3'-sulfamoylacetophenone

Product 1

HCID 22760449HCID 22760449, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

3.1 g of 2-bromo-4'-chloro-3'-sulfamoylacetophenone and 1.3 g of 4,4-dimethyl-2-imidazolidine-thione were reacted as described in Example 12 in 15 ml of methanol, the reaction mixture was precipitated with 70 ml of diethyl ether and the oily precipitate was crystallized with ethyl acetate at 40° to 50° C. Colorless, crystalline solid body: melting point: 164° C (decomposition).

Workup

  1. customthe reaction mixture was precipitated with 70 ml of diethyl ether
  2. customthe oily precipitate was crystallized with ethyl acetate at 40° to 50° C

Sources & evidence

ORD record
ord-6d567a643e8b45d3977e2d9564a01522
Source dataset
uspto-grants-1977_12
Patent number
US04061761

Reaction notes

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