HCID 3788169, compound → HCID 22760445, compound

HRID 461139Notes

Reaction equation

HRID 461139 reaction equation
[Br:1][CH2:2][C:3]([C:5]1[CH:10]=[CH:9][C:8]([Cl:11])=[C:7]([S:12](=[O:15])(=[O:14])[NH2:13])[CH:6]=1)=[O:4].[Cl:16][C:17]1[CH:28]=[CH:27][CH:26]=[CH:25][C:18]=1[CH2:19][NH:20][C:21]([NH:23][CH3:24])=[S:22]>>[BrH:1].[Cl:11][C:8]1[CH:9]=[CH:10][C:5]([C:3]2([OH:4])[CH2:2][S:22][C:21](=[N:20][CH2:19][C:18]3[CH:25]=[CH:26][CH:27]=[CH:28][C:17]=3[Cl:16])[N:23]2[CH3:24])=[CH:6][C:7]=1[S:12](=[O:15])(=[O:14])[NH2:13]

Participants

3

Reactant 2

HCID 3788169HCID 3788169, compoundHCID 12952390Bromo-4'-chloro-3'-sulfamoylacetophenone

Product 1

HCID 22760445HCID 22760445, compound

Procedure

4.7 g of 2-bromo-4'-chloro-3'-sulfamoylacetophenone and 3.1 g of 1-(2-chlorobenzyl)-3-methylthiourea were reacted according to Example 23 and the crystalline end product was filtered off. Colorless crystalline solid body: melting point: 182° C (decomposition).

Workup

  1. filtrationthe crystalline end product was filtered off

Sources & evidence

ORD record
ord-b753e67c99614cbfa06ba0d655c67467
Source dataset
uspto-grants-1977_12
Patent number
US04061761

Reaction notes

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