HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[2-(4-Methyl-3-nitrophenoxy)ethyl]morpholine → 2-Methyl-5-[2-(morpholin-4-yl)ethoxy]aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[2-(4-Methyl-3-nitrophenoxy)ethyl]morpholine | HCID 58929867 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-Methyl-5-[2-(morpholin-4-yl)ethoxy]aniline | HCID 39335039 | — |
Reaction Steps
To the mixture of 4-(2-(4-methyl-3-nitrophenoxy)ethyl)morpholine (532 mg, 2 mmol) in MeOH (50 mL) was added 10% Pd/C (250 mg). The mixture was stirred under an atmosphere of H2 (balloon) overnight. The contents of the reaction mixture were then filtered and concentrated in vacuo to give the title product, which was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08541592B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-b92268b26e0144e1b41cb66cb5379de2 |
| Source note | uspto-grants-2013_09 |