HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,N'-Diethylthiourea → 3-Ethyl-2-ethylimino-4-(4-methyl-3-sulfamoylphenyl)-1,3-thiazolidine-4-ol-hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,N'-Diethylthiourea | HCID 2735009 | — |
| Reactant | 2-Chloro-4'-methyl-3'-sulfamoylacetophenone | HCID 13628783 | — |
| Solvent | Diisopropyl Ether | HCID 7914 | — |
| Product | 3-Ethyl-2-ethylimino-4-(4-methyl-3-sulfamoylphenyl)-1,3-thiazolidine-4-ol-hydrochloride | HCID 22760433 | — |
Reaction Steps
5 g of 2-chloro-4'-methyl-3'-sulfamoylacetophenone and 2.7 g of 1,3-diethylthiourea were reacted as prescribed in Example 12. After addition of 200 ml of diisopropyl ether the solvent was decanted and the oily end product was crystallized under ethyl acetate heated to 40° to 50° C. Colorless solid body, melting point: 160° C (decomposition).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04061761 |
| Source dataset | uspto-grants-1977_12 |
| ORD ID | ord-31fcc2290c774320bcc607a62f00ec11 |
| Source note | uspto-grants-1977_12 |