HuagongsheHuagongshe Chemistry Print Report · For research reference only
Allylamine → 4-(3-Allylsulfamoyl-4-chlorophenyl)-3-methyl-2-methylimino-1,3-thiazolidine-4-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Allylamine | HCID 7853 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-Chloro-3-chlorosulfonylphenyl-3-methyl-2-methylimino-1,3-thiazolidine-4-ol-hydrobromide | HCID 22760489 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-(3-Allylsulfamoyl-4-chlorophenyl)-3-methyl-2-methylimino-1,3-thiazolidine-4-ol | HCID 22760442 | — |
Reaction Steps
8.7 g of 4-(4-chloro-3-chlorosulfonylphenyl)-3-methyl-2-methylimino-1,3-thiazolidine-4-ol-hydrobromide were reacted as prescribed in Example 76 with 1.5 g of allyl amine and 4 g of triethyl amine in 50 ml of ethanol and worked up. The water was decanted and the amorphous end product was crystallized under diethyl ether. Colorless solid body, melting point: 146° C (decomposition).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04061761 |
| Source dataset | uspto-grants-1977_12 |
| ORD ID | ord-83df1c62f21744b6b2ef8a1d2d41414e |
| Source note | uspto-grants-1977_12 |