HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 4-(4-Chloro-3-cyclopropylsulfamoylphenyl)-3-methyl-2-methylimino-1,3-thiazolidine-4-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Cyclopropylamine | HCID 69828 | — |
| Reactant | 4-Chloro-3-chlorosulfonylphenyl-3-methyl-2-methylimino-1,3-thiazolidine-4-ol-hydrobromide | HCID 22760489 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-(4-Chloro-3-cyclopropylsulfamoylphenyl)-3-methyl-2-methylimino-1,3-thiazolidine-4-ol | HCID 22760448 | — |
Reaction Steps
6.6 g of 4-(4-chloro-3-chlorosulfonylphenyl)-3-methyl-2-methylimino-1,3-thiazolidine-4-ol-hydrobromide were reacted as prescribed in Example 76 with 1.5 g of cyclopropyl amine and 4 g of triethyl amine in 50 ml of ethanol and worked up. Fair yellow crystals, melting point: 180° C (decomposition).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04061761 |
| Source dataset | uspto-grants-1977_12 |
| ORD ID | ord-55156e1694c34522a2798eed7fc11fe2 |
| Source note | uspto-grants-1977_12 |