HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Pyridinemethanamine → 4-[4-Chloro-3-(2-picolylsulfamoyl)-phenyl]-3-methyl-2-methylimino-1,3-thiazolidine-4-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Pyridinemethanamine | HCID 19509 | — |
| Reactant | 4-Chloro-3-chlorosulfonylphenyl-3-methyl-2-methylimino-1,3-thiazolidine-4-ol-hydrobromide | HCID 22760489 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | 4-[4-Chloro-3-(2-picolylsulfamoyl)-phenyl]-3-methyl-2-methylimino-1,3-thiazolidine-4-ol | HCID 22760540 | — |
Reaction Steps
8.8 g of 4-(4-chloro-3-chlorosulfonylphenyl)-3-methyl-2-methylimino-1,3-thiazolidine-4-ol-hydrobromide were reacted with 3.0 g of 2-picolyl amine and 5 g of triethyl amine as prescribed in Example 76 and the end product precipitating as crystals was filtered off. Melting point: 166° C (decomposition).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04061761 |
| Source dataset | uspto-grants-1977_12 |
| ORD ID | ord-44c3ab0643b44b2f912231ba9939241f |
| Source note | uspto-grants-1977_12 |