反应详情

A solution of 8.16 gm. (0.05 mole) of 2-amino-5-nitrobenzonitrile and 9.28 gm. (0.05 mole) of m-nitro benzoyl chloride in 50 ml. of dry pyridine is refluxed for 3 hours. The pyridine is removed by distillation in vacuo and the solid residue triturated with water. There is obtained 15.3 gm. (95%) of a yellow solid that melts at 203°-205°. Recrystallization from aqueous ethanol (2:1) gives material melting at 205°-206°.

1. customThe pyridine is removed by distillation in vacuo
2. customthe solid residue triturated with water
3. customThere is obtained 15.3 gm
4. customRecrystallization from aqueous ethanol (2:1)