HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Dichloroethane → 4,5-Dichloro-2-octyl-1lambda~4~,2-thiazolidine-1,3-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Dichloroethane | HCID 11 | — |
| Reactant | Sulfuryl chloride | HCID 24648 | — |
| Reactant | 2-Octyl-1H-1lambda~4~,2-thiazole-1,3(2H)-dione | HCID 15960475 | — |
| Product | 4,5-Dichloro-2-octyl-1lambda~4~,2-thiazolidine-1,3-dione | HCID 12318233 | — |
Reaction Steps
To a solution of 2.29g. (0.01 mole) of 2-n-octyl-4-isothiazolin-3-one 1-oxide in 3 ml. of EDC is added 1.2g. (0.01 mole) of sulfuryl chloride in 3 ml. of EDC. The mixture is stirred at room temperature over a weekend. The solution is filtered and concentrated to give an oil. The oil is further purified via column chromatography (100% benzene: silica) to give 1.0g. (33%) of product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04062859 |
| Source dataset | uspto-grants-1977_12 |
| ORD ID | ord-3e9c50825294447eb3d815dacd4134a0 |
| Source note | uspto-grants-1977_12 |