HuagongsheHuagongshe Chemistry Print Report · For research reference only
M-Cresol → m-Cresyl 3-indolylglyoxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | M-Cresol | HCID 342 | — |
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 3-Indoleglyoxylyl chloride | HCID 89952 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | m-Cresyl 3-indolylglyoxylate | HCID 21393607 | — |
Reaction Steps
3-Indolylglyoxylyl chloride (104 g. ) was stirred in diethyl ether (500 ml.) and treated with m-cresol (108 g.) followed by pyridine (79 g.). After stirring for 30 minutes the solid product was collected by filtration, washed with water then with acetonitrile and dried to give m-cresyl 3-indolylglyoxylate as a yellow powder, m.p. 194°-197°. Yield 119 g. (85.5%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04062869 |
| Source dataset | uspto-grants-1977_12 |
| ORD ID | ord-934fc004b6e84a2bb6c09c3080607a5b |
| Source note | uspto-grants-1977_12 |