HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methylindole → 62454-47-1
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methylindole | HCID 7224 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 2-Methyl-α-oxo-1H-indole-3-acetyl chloride | HCID 12392196 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 62454-47-1 | HCID 11769588 | — |
Reaction Steps
A solution of 2-methylindole (32.8) in diethyl ether (300 ml.) was added at 30° to oxalyl chloride (35.0g.) diluted with diethyl ether (200 ml.). After stirring for 1 hour the precipitate of 2-methylindolylglyoxylyl chloride was collected by filtration and treated with methanol (300 ml.) to give the methyl ester of 2-methylindol-3-ylglyoxylic acid (30.0 g.) as a red powder m.p. 180°-183°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04062869 |
| Source dataset | uspto-grants-1977_12 |
| ORD ID | ord-828ad899fab9448fb28678ea726f6d6f |
| Source note | uspto-grants-1977_12 |