Hydrochloric Acid → HCID 53679806, compound

Participants

Reaction Steps

3-(2-Amino-ethylcarbamyl)-5-nitro-benzoic acid (200 g; 0.79 mole) is dissolved in water (1000 ml) and concentrated hydrochloric acid (75 ml). Palladium-over-charcoal (20 g) is added thereto, and the material is hydrogenated in an autoclave during 2 hours, under a hydrogen pressure of 3-4 kg. The resulting material is filtered and evaporated to dryness in vacuo, to give a solid which is taken up into ethanol (500 ml). The resulting precipitate is suction filtered, washed with ethanol and dried, to give 130 g (Yield = 74%) 3-(2-amino-ethylcarbamyl)-5-amino-benzoic acid the purity of which is controlled by:

Provenance & Evidence